I had no side effects of herceptin at all, if that helps. Wasn't mad on taxol but by the time you get to the 6th dose you are halfway through! Reactions vary wildly and as primek says, you won't really know how you go till you start. I worked throughout, others had a tougher time. If it's any comfort about your hair, it often feels quite alien before it goes. Most of us went for a shaved head or the number 3 clippers before everything got messy. My hair started growing back while I was still on taxol, which was unexpected but good! Good advice to concentrate on what's happening now and not spend too much time anticipating things that may not happen. Cancer treatment takes a fair bit of energy so keep it for the right things - those that support and care for you, looking after your own sense of purpose and strength, and not losing sight of the brighter things of life as you work to get well again. Good luck!