ER -ve DCIS have had Tamoxifen offered
Hi brains trust. I have just had single mastectomy due to high grade and large DCIS. The results from pathology show that the DCIS was ER/PR-ve and HER2 +ve. I’ve been offered Tamoxifen as an option to reduce risk on other side. Am I right in thinking this would not help if I get the same kind of DCIS or cancer in the other side? I’m not sure how keen I am to take hormone blockers as my understanding is that I now have same risk as the rest of the population. Anybody else been in this situation? Any suggestions on where to research?
How to continue my ongoing oncology care in SYDNEY??
Hi! I was diagnosed and treated for early stage breast cancer (DCIS grade 1, ER+ PR+) at 29 y/o, a few months ago, in Sweden where I work. I had planned to move to Sydney in September (my husband got a job there) but before doing so, I need to make sure that I can properly continue my endocrine treatment in Sydney: 1) Anyone knows what is the fastest/cheapest way to get my Letrozole prescription +injections of Zoladex (Goserelin) every 4 weeks? I need to make sure that I can get the injections on time once I moved to Australia. I found the cost of both medicines on PBS website but what is the cost of the doctors appointments (to prescribe and to inject Zoladex)? 2) Is it also required to do a blood test (to check hormon levels) every months when you take Zoladex? Note: I am not Australian but I will get the yellow Medicare card (due to a health agreement between Australia and Sweden). Thanks in advance for your help!! I hope I will be able to relocate to Sydney and live my life as before... :smile:
Aromatase Inhibitor (AI) vs Tamoxifen for premenopausal women
Hi all, I've been diagnosed with invasive ductal carcinoma, stage 1a, grade 2, ER and PR positive, HER2 negative, nodes all clear. Age 35. As I also found out that i am BRCA2 positive, I will also be undergoing a bilateral mastectomy. As the cancer is hormone receptor positive, I will need to start hormone treatment after surgery. I have consulted two oncologists and they have slightly different approaches: Oncologist 1 - Aromatase Inhibitor + monthly injections of Zoladex (start both concurrently) - the results from the recent SOFT trial indicate that the combination of Zoladex + AI is more successful at preventing a recurrence of cancer. - the downside could be that the side effects could include muscle and joint stiffness. Oncologist 2 - Tamoxifen + monthly injections of Zoladex (start with Tamoxifen first, then after a few months if all good, then start Zoladex) - gradual approach to minimise impact to body Are there any pre-menopausal ladies who are either on Tamoxifen + Zoladex or AI + Zoladex who could share your experiences? What was your reason/rationale for choosing either option..? What are the side effects that you have experienced..? Many thanks in advance.
Tamoxifen
Hi there, I have had a left breast mastectomy on the 9th of August 2011. Two tumors, 8 mm and 10 mm, as well as a 4 mm area of DCIS was removed. Luckaly both tumors where Grade 1. There was no limfnode involvement, 7 was removed. I chose to have a mastectomy, rather than just to remove the tumor area, as this meant I would not need to have radiotherapy after the surgery. Because there was no limfnode involvement, chemotherapy was not recommended. What a releave! Tamoxifen however is indicated as the tumors are receptor positive for estrogen and progesterone. Reading about the side effects of tamoxifen has really scared me! I am only seeing the oncologist on the 29th of September, but I am really thinking of declining the Tamosifen treatment. Any commends, recommendations, or opinions on this will be appreciated. Thanks!