I don't know much about the type of chemo you're having as I had AC-T. One of the things that I came to realise is that chemo is a pretty blunt instrument and the dosage you're given is not to do with it being the minimum safe dose but the maximum safe dose. So, quite possibly (and I say this with no experience of TC), 3 out of 4 might be all that is required (unknown) with 4 treatments being the maximum the average body can reasonably tolerate. I started getting PN in some of the toes on my right foot around taxol 8 or 9. By the time I reached No. 12, it was going up both legs and in my fingers. While most of it recovered fairly quickly after chemo, the original PN response in those toes remains. I can't answer for you but, also having school-aged kids, survival has always been paramount for me. However, being crippled with side effects is not much of a survival. If it were me, I would question my onc closely about how much benefit is KNOWN for having the complete 4 treatment cycle, and unless it was significant, I would pull the pin on it before the PN has the possibility of causing permanent debilitating damage. If the benefit is known to be huge, I would at least ask about a longer break to let symptoms settle down, but possibly still stop. But I can't really answer for you. Whatever your decision, it has to be something that you can live with.