I'm not so sure that what you paint on top of the nail (which is in any case dead nail tissue) has that much of an effect. The poisoning to the living nail bed is systemic throughout the whole body and that is where the majority of the damage is done. The advise on painting the nails with a dark polish may block out the UV rays from sunlight, but other than that, I have found no scientific evidence to show this is effective. There is anecdotal evidence where some patients have said that they painted their nails black or blue or whatever, and had little or no damage, but they might in any case have been one of those fortunate people to escape yucky nails. I would be more interested if a large cohort of patients painted only one hand, throughout treatment, and then afterwards, compared both...or each alternate nail, both left hand and right so there could be no later claims of left side/right side preference of dominant versus non dominant hand and associated wear and tear damage.