Hi @van68, it's awful isn't it. My suggestion us to just go with it. Don't try to sleep. I am ok with sleep most nights with a change of meds from tamoxifen to Letrozole. However when on tamoxifen I use to wake up every night. I started with tossing and turning and trying to get back to sleep. In the end I just read or watched TV. I would stay up for an hr or 2 and then I was able to sleep again. It's hard, most definitely but for me it was more distressing trying to sleep so hence just being awake, sweat it out and then start again. I use to be awake from about 1am to 3am every morning. Good luck, keep trying different strategies and hopefully one of them will work. Ps: I did have a friend who resorted to sleeping pills.