Hi Cate , I was talking to another lady in the waiting room at the pathology department yesterday . She said she has been on Xeloda now for 2 year for lungs mets after breast cancer . She seems to be going okay. She found that Vaseline rubbed into the feet at night and to put on cotton socks worked well for her feet problems. I was Xeloda over two years ago but had to come off the drug after 18 months due to sore feet. I wish I had know about the Vaseline, I might have coped better. It is still a drug that I can go back on, after a break. It is a good drug and seems to bring the tumor markers down. Remember every one is different and the treatment effect people differently. Stop worrying!