Hi all. I resorted to filing my feet myself because the podiatrist made them soooo bad that I couldn't stand or walk for over three weeks. At least I can do a little filing occasionally and manage how much I take off -- but it is a learning curve -- and thereby avoid getting the big 'scales' and cracks that catch on my socks then tear, which is not nice! The oncologist was happy and encouraged me to file my feet for myself. I think it is a matter of what can be managed best.
Yes, getting the drug balance right to minimise side effects while hopefully maximising cancer control takes a bit of time. I started out over five years ago on five tablets morning and night (I'm a tall woman) and it has slowly dropped to two morning and three at night. When I've accidentally (or intentionally to vary my week off dates) extended my two week drug time, just three or four doses (one to two extra days) is enough to wind up side effects. So, what I'm saying is don't mind about the slow drop in dose, and keep doing the cool hands/feet, no friction, cotton sock/gloves, moisturising routines because they do help. Hope that's encouraging :)