Hi Moira. I had neuropathy after IV chemo but it did gradually improve. And while Xeloda hands and feet are a pain, for me I've found that I've got used to it and know what I can and can't do. Yes, there's a sort of background burn that is there all the time but if I'm careful it stays just that, background. Absolutely no friction on skin allowed and plenty of grease! I've also found getting enough rest makes it all fairly bearable. I've been doing cross-stitch tonight and had a long slow careful walk in the beautiful weather today. Xeloda is still working and I'm still a fan! :) Hope all goes well, and also for you Elaine.