Hi Tralee, I am new to Xeloda too. I am on my 4th cycle. I started taking 4 x 500 morning and night, but cut back to 3 x500 morning and night whilst I had radiation on my sacrum for bone mets. I am now on 3 x 500 morning and 4 x 500 night. My onc said it is accumulative so side effects may become more pronounced each new cycle. I do get diarrhea about the last 2 days. Through the rest of the two weeks it can depend on what I eat (cant help being naughty sometimes). I have found that I get heartburn more regularly now but try to remember to take a tablet to help this before my meal.
My skin has been ok so far, no splitting on my hands or feet. I find that my sleep is disrupted on the tablets and the further into the two weeks the more I get a foggy brain. I am tired a lot but still working full time. The tablets have started to work on bringing my markers down, slower than I would like though. I hope that you get your desired results. Stay positive and keep fighting.
