Shades of Grey

Jennt28 - I too am hoping it is some sort of inflammatory response to the drugs and maybe some tumor flare. I have only my past experiences to go by and the only time I have had reduction of disease it happened very quickly and my tumor markers halved in response to the meds - this response while quick was not sustained. I do have options left but with each treatment "failur" that list gets smaller. I seem to have a particularly fhemotherapy resistant cancer which is not well controlled either with herceptin. I am hormone negative so I have no hormone treatment options. Being on a trial I have to go with trial guidelines. So yes, if I get a result that puts the growth of the target lesions at the 20% mark or there is any sign of new disease I will be bumped from the trial regardless of whether the disease progression has been slowed significantly. My most likely next option is another drug which is currently not available to us in Australia and is not in any trials I can access. I can appeal for compassionate use but it is rarely granted. So for now, I am focused on enjoying christmas and getting the most out of this one. A x