Olaparib / PARP inhibitor
Does anyone have experience with Olaparib (or other PARP inhibitors, suited for women with BRCA mutations)? I may be taking it later in the year (after 8 months Abraxane) and just wanted to check the ...
Forum Discussion
I am currently partcipating in the Embraca clinical trial and I was lucky enough to be assigned the trial drug, Talazoparib - also a PARP inhibitor.
I've been on it since late December and in terms of side effects, it hasn't been that bad.
My blood work shows that I am tolerating the drug, so no dramas there.
I did notice a loss/thinning of hair in the beginning and it hasn't grown back or rather, it grows back slowly i.e I had long eyelashes now they are short and stubby, my eyebrows are sparse/patchy, I don't book waxing appointments as often and I changed my hair style because it really thinned out at the temples.
I did feel nauseous and tired during the day when I took my medication in the morning or just before bedtime. I now take the drug in the early evening/before dinner and I don't feel nauseous anymore. I do tend to feel tired in the early evening and sometimes go to bed at 8pm or so. I never wake up feeling refreshed.
I am really struggling with pain at the moment at the sites of my bone mets but I don't think this is a side effect of the trial drug. I just need to get my pain meds sorted.
I hope this helps.
I've been on it since late December and in terms of side effects, it hasn't been that bad.
My blood work shows that I am tolerating the drug, so no dramas there.
I did notice a loss/thinning of hair in the beginning and it hasn't grown back or rather, it grows back slowly i.e I had long eyelashes now they are short and stubby, my eyebrows are sparse/patchy, I don't book waxing appointments as often and I changed my hair style because it really thinned out at the temples.
I did feel nauseous and tired during the day when I took my medication in the morning or just before bedtime. I now take the drug in the early evening/before dinner and I don't feel nauseous anymore. I do tend to feel tired in the early evening and sometimes go to bed at 8pm or so. I never wake up feeling refreshed.
I am really struggling with pain at the moment at the sites of my bone mets but I don't think this is a side effect of the trial drug. I just need to get my pain meds sorted.
I hope this helps.