Hi Angg66, I was on Abraxane 5yrs ago when first diagnosed with mets. in the bones. I had 6 cycles of 3weeks on and one week off. It worked well keeping the cancer stable and some areas shrunk in size. It also brought my tumour markers way down. Since then I have been on Xeloda, Aromison, Affinitor, which all worked for a while. Now I'm back on Abraxane and last scans where stable, with tumour markers tumbling again. Side effects are not too bad . Tiredness for a few days after, mild neuropathy of fingers and toes. My main problem is constipation from the anti nausea drug they give you in the drip. Some weeks are better than others. The best part is when you have a week off to recover. I really make the most of that week. Hope you go well.