Zoladex

Hello @Newbie3312,

I was on Tamoxifen for five months then had to switch to Zoladex plus Letrozole two months ago. The initial sudden drop or disruption of hormones on any of these drugs is tough. I had severe joint pains, bad insomnia and mood swings in the first weeks on Tamoxifen. It gradually settled down. The switch to Zoladex was fairly uneventful, probably because I had already been on the Tamoxifen. I have noticed joint soreness on Zoladex,/letrozole, but keeping active helps to keep it at bay. I hope you feel better soon. :)

I had no problems with Zoladex apart from one hiccup in 2 years.  I think your thought process of adrenaline and working hard are possibly contributing to how you are feeling.  You have been through a lot and need time to reflect and take it all in.  Fatigue is normal and perhaps pushing yourself has brought on the emotions!
  
https://www.bcna.org.au/health-wellbeing/physical-wellbeing/fatigue/

Best wishes with treatment

Hello @Newbie3312

I’m on Zoladex, I had my third injection a couple weeks ago. I was initially worried about side effects, but have to admit I’ve been feeling quite free and wonderful not having 7 day periods, and PMS that sometimes lasts 2 weeks prior to period starting. So I caught myself actually enjoying it 😮. I do have the occasional hot flush, but they’re short and not very frequent. I do also have moments when I just wanna cry, and I do cry, and I get angry and throw tantrums, but it’s not connected to the Zoladex. It’s just the whole bc thing, daughter not listening, shitty covid situation that gets to me at times. And the fact I still need to deal with getting the bc, even though I’ve accepted it and am mostly ok and moving on with life and generally happy. Now, I did have my first Letrozole tablet today, so we’ll see. I’m hoping not much changes 🤞. And I do have a left shoulder that’s in massive pain, but I think it’s due to a bad sleeping position. 

Thanks everyone. Possibly appears I’m just a bit run down and failing to keep my S$&t together 😂🤦‍♀️

Hello 👋 I have a question just started on zoladex nearly a week and have been in tamoxifen I month. I’ve had no periods since yet today I’m spotting and have done discomfort. I’m thinking it’s the zoladex kicking in with my ovaries as I think I recall the nurse saying this may happen early but as you can imagine it’s hard to take it all in? 

Hi, im not on tamaxofin only zolodex and that is consistent with my symptoms. Ive been on 2 months and happened both months to date.

Some hormone emotions like normal cycle too.

Hope it helps. 

Michele

Thanks 🙏@MicheleR it helps to her they and feel somewhat normal x 

@NelSky I had spotting first month of zoladex and started tamoxifen a month ago. I haven’t had a period since first month of zoladex I’m in month 4 now 😊

@Newbie3312 how are you finding you cocktail 🍹 of drugs ?? 

@NelSky not great. I am taking a lot of pain killers for arthritis in neck and have quite sore joints from tamoxifen. I take a lot of supplements as well. It’s tough but obviously could be so much worse. I just remind myself every day when I have tablet it’s keeping me healthy.