I'm 18mths into Tamoxifen.
It's been brutal but I get depression, so how much of it is that, how much is early menopause and how much is the Tamoxifen, I can't say.
I'm very tired (struggling to hold down a job) and very angry. I feel it does make my bouts of depression worse. But, as I said above, that could be menopause.
Tamoxifen does keep your bone density up, which is an advantage over other meds. With so many aspects of cancer treatment creating other health problems, it's nice to have a win.
I keep on it due to that and sheer stubbornness.
My cousin in the uk, who is undiagnosed bipolar, ended up stopping Tamoxifen because she said it made her crazy. She went to an aspirin trial.
If it's recommended for you, give it a good try and see how you go.