I have been on both Tamoxifen and Zoladex for over 1 year and have really struggled with all of the side effects. I started Tamoxifen in August 2019 and added in the Zoladex in November 2019. It's hard to know which drug to attribute the symptoms to. I have to try and get to 2 years on the Zoladex and then I can stop... I came very close to giving up during the COVID lockdown this year but my Oncologist has convinced me to continue on it for now. If I have to be honest, the only thing getting me through is knowing there is an end date to the medication! It's a hard slog but we are strong :)