I think I've been on about 5 different brands of letrozole over the 14 months I've been on it, the current one being Fera by Aspen Australia. I've not noticed a difference in any of them side effect wise. The latest achy pain that has got worse is in my right thumb joint spreading into my wrist and arm area. I'm so thankful that i had both my carpal tunnels done pre BC otherwise I'd really be up the creek without a paddle. Yes if i overdo it in the garden i pay for it but ice packs generally do the trick. I do try to let my left hand do more but i can feel the same thing happening in that hand too...damned if i do danmed if i don't! Taking pain relief is a last resort as i have enough issues digestion wise without adding those to the mix. If i keep my hands moving it helps, it's when they are locked in position like driving for over an hour that they seize up as well as my hips...and ankles... and knees...grrrr. i don't think changing brands has been the issue. I am seriously considering taking a break from the drug over winter as i could barely my hands last winter...a chat i will be having with my onc in April. Surprisingly all the weight work i do in gym helps my hands mobility but it's not a lasting fix. As much as i would love to do gym more often i know i can't...must have a days rest in between. One good thing, the hot flushes have eased to almost nothing, hope it stays that way. Good luck Romla.
