@Romla something that wouldnt have been mentioned is that for some reason Prolia guards also against Breast Cancer. So I look at that and think ok LOL, an extra bonus. Not sure what sort of reviews you read, but I've been on Prolia a year and havent noticed anything to do with that at all. Interesting thing is, alot of side effects or symptoms come from a combination of things not just one thing. My pain I know comes from chemo, fibromyalgia and Aromasin. My Hot flushes actually started through chemo being thrown into menopause, Ive been on and off medication and made no difference to that, they are purely menopause. So everyone has a different perception of what causes their side effects for them. I did have a look at some reviews just now, but honestly I've not experienced anything like that. I may be a little sore the day after but that's it.