It is hard to say what side effects are Tamoxifen and what in my case is just menopause. I did get lots of bone aches but a year on Tamoxifen and that pain is mostly all gone so that's good. I am still having heaps of hot flushes and for some silly reason I have trouble regulating my own body temp which is annoying. Moodwise we all have our ups and downs and after what we've been through with our world turned upsidedown its understandable but its not permanent even on Tamoxifen. Little hint with the tabs, get your oncologist to double the script from 30 tabs to 60. It saves refilling the script monthly and you get a little discount for two boxes instead of one. Often they are out of stock too so don't leave it to the last pill left.