Hi Ladies, I was diagnosed with breast cancer in august 2012, and have just started taking tamoxifen,I have only been taking tamoxifen for six days and I have already had enough, how am I going to cope for the next five years.. Hot flushes all the time especially at night time so not getting much sleep. stomach aches, really saw legs, but worst of all my moods, Iam so depressed I dont want to talk to anybody and I actually really hate my Husband !! ( mm poor thing ) My poor kids think mum is loosing it, everything makes me angry even the smallest things, how long does this last or is it just me?