Hi Angie
I'm peri-menopausal and have been on Tamoxifen since February.
My breast surgeon said that usually Tamoxifen side effects are greatest in the early stages of taking it.
The only symptoms I seem to have are hot flushes (which I was starting to have anyways) - which usually come at night and seem to go from my ankles to my neck! Other than that, it's been pretty plain sailing....I am doing lots of exercise (pilates, walking and running on treadmill) to try and keep joints flexible and abate any of the weight-gain side effects.
My GP will get me to have an ultrasound within 12 months to check on the lining of the uterus, just as a check.
I take mine in the morning.
Nikki