I can sympathize @iserbrown. I have recently started having extremely painful calf cramps in my right leg. I have been back on tamoxifen for almost 2 years so am not sure it is related for me. I already take magnesium and eat potassium rich foods. The only major change I have had in recent times is an increase in stress and an injury that prevents me from walking for exercise. I have just started acupuncture for the injury and the acupuncturist asked me, as she was treating me, if I suffer from calf cramps. I will ask her next visit what she thinks is causing the cramps. I am hopeful the treatment she is giving me might settle them down. My calf is constantly sore from them at the moment. I am also getting cramps in my foot/toes on the same leg when I try to stretch on that side.