Hi Lisa. I can't believe the drug companies have never done proper studies into dosage. My Oncologist said it was not in their interest. We are all different, our physiology is different. If you are able to hang in there it is the best thing to do according to Oncologists. However, I did read only 42% of women complete the 5 years so you have to wonder where they get their "percentages for survival taking them". I really tried to take them but found the side effects negated any quality of life -they especially impacted on my mental health. Had I stayed on them I would have lost everything. I have thought about it long and hard and wondered how I would feel if I was one of the statistics that got secondary breast cancer. How would I feel then? Would I be filled with regret? But then I thought, probably not - I couldn't have survived on the meds anyway and it doesn't guarantee you won't get secondary breast cancer anyway - so how would I know? Anyway, good luck - keep going with it if you can. Suexx
