@bevvzy. I had been on Warfarin for 17 years prior to being diagnosed with my breast cancer. I was taken off the Warfarin and put on Clexane injections twice daily for the biopsies and then kept on that during my six months of chemo. 12 Weeks of AC therapy, followed by 12 weeks of Taxol and Herceptin...the Herceptin will continue for another few months yet. I am having my surgery in threed days time (double mastectomy with full none clearance on the left and sentinal nodes on the right...possibly more on the right, depending on the pathology whilst I'm still in theatre). So I'm still on the Clexane until after the surgery, and I too, will go onto hormone blockers afterwards. Don't know yet if I'll stay on the Clkexane (ouch) for the next ten years, or if they'll put me back on the Warfarin...depends if the hormone blockers muck around with the INR I suppose. I've also had PE's and repeat DVT's, (even on Warfarin), prior to this particular Sh*t Fest.