I too have a numbness to the balls of my feet and the middle toes on both feet. For me this isn't related to the chemo, as it was happening before cancer. My podiatrist told me that the metatarsal joints on my feet had started to collapse due to high heel wearing in my youth. It is a weird sensation, and I notice it more when in bed, when it seems like I have a ball of cotton wool wedged under my toes. They aren't completely numb, but the sensation is definitely altered, and it s getting worse. It is hard for me to know if the chemo has added to it, or if it is just degeneration. Love Chris