I’ve been on Letrozole nearly 2 years. I did have joint aches at the outset but found daily walking for an hour enabled me to walk thru it I think.I do notice it if I don’t walk as my joints seem to seize up a bit.I also take 1 Krill Oil capsule daily at the recommendation of my prescribing oncologist Dr Selva.
I too have vaginal atrophy which is problematical as I have to have annual Pap smears which are difficult to perform , uncomfortable and getting a result difficult.I use Vagifem pessaries for 5 days prior to my pap which helps esp in getting a result.
That said I have had 2 other health issues which MAY be related to Letrozole.I had glaucoma in one eye for a few years prior to starting Letrozole and my eye pressure spiked necessitating a series of operations . The non operated eye has recently had a vitreal detachment which is mainly problematical as it carries a risk of retinal detachment.I know from my reading that Tamoxifen carries eye side effects and wonder if AIs do too but is as yet underresearched as they are relatively new.
The second issue may also be related to Letrozole I have had a painful tennis elbow which has made dressing , preparing meals and even opening doors difficult.Tennis elbow is a tendon injury and have noted many on here taking Letrozole speaking of trigger thumb and carpal tunnel.