I am on Tamoxifen and probably going to change to Letrozole in two months. Not looking forward to it although I sort of am if it will knock off some of the side effects of the former. Yes I have bouts of tears (which I suppress) and depression. I find it can be a monthly thing even though I haven't had a period in years. My body is still figuring out menopause. Sometimes the tears sneak up on you for no apparent reason. I was in the movies and a trailer came up of MaMaMia2. For no reason the music had me crying. How embarrassment. To this day I have no idea why it upset me.