Hi @SamL890 I am so sorry to read about the impact you’re experiencing- I encourage you to follow up about the Letrozole. Although not as severe as your situation sounds, I have some aches in my ankles and legs since being on Letrozole (I started in March). The aches come on in the early evening.
For reasons of travel I am going to take a few weeks break from Letrozole - with my oncologist’s agreement - we both think it will be interesting to see what happens.
I hope your nurse can support you in approaching your oncologist as I’ve found mine to be very open to considering the range of hormone therapy medications to see if there is one that suits me better.