Hi Vanessa
I have been Herceptin long term as I am stage 4 HER2+ ER+ my mets are in the lungs apparently Herceptin and Femara together was the best option for me and it has worked great until now.
Because I am also on Femara it is hard to say which medication causes what side effects but I have really bad hot flushes which I am told is Femara as well as joint pain. I do know Herceptin has caused the dry sore nose and fatigue. All the side effects are manageable even the hot flushes although sometimes they are still really bad.
Good luck with your treatment it is a wonder drug and I am sorry I can't continue with it.
Sue