Hi, I will be asking my medical oncologist about this when I next see him - after my chemo is complete. I have been on Tamoxifen for 4.3 years until I was re-diagnosed in December. I was immediately put on Arimidex which of course can leach our bones of calcium. Whilst on chemo I have been taken off the Arimidex but will most likely commence after next consultation with MO. So many things to consider - one drug helps with one thing but there is alway side effects. I am always mindful of my bones and in my "normal" life do lots of weight resistance to strengthen them. I suppose, like you, we can only keep doing what we think is helping us lead better lives. XLeonie