I'm on AI and had osteopenia before starting. I'll be watched closely and start prolia if gets too low. I initially had stiffness in ankles abd wrists which improved once moving around but it settled after a few months. I had some memory issues for a little while post chemo but that seems to have resolved now. I think stress contributed to this also and fatigue. I think of it as my insurance pill at keeping any remaining cells at bay (and we all hope there are none ) and hope they just starve to death. Hope all goes well. I'm on letrozole. Kath x