What are Ki67 and Oncotype tests?

Hi @Abbydog, the Ki67 is a pathology test on the breast tissue removed. Basically it is a protein and is an indicator of how quickly the cancer goes. A high Ki67 is a fast growing and high percentage of cancer cells in the breast tissue removed. I had a very high Ki67 result on my pathology report and hence chemo was recommended as part of my treatment.

Thanks Cath62
It’s only for my curiosity. Is the Ki67 standard histopathology? My Dr never spoke of it. But I was told it was Grade 3, which I was told means the fastest growing from grade 1-3.  Maybe he simplified it for me. Thank you for your reply. I have not understood what other ladies have been talking about. I’m not unhappy about my treatment. Although not enjoying the AI’s

@Abbydog , I had a copy of my histopatholgy report and my surgeon oncologist explained it all.  I had grade 3 too. I am an ex nurse and my treatment team could discuss things in a bit of detail with me because of that. Maybe you Dr thought that they covered enough.  

I didn't have the oncotype test, unless I wasn't aware of it. Its a predictor type test which gives an indication on whether the breast cancer is likely to spread elsewhere. 

Thanks. 

I had a high score ki 67 score it was 58% but oncoytype came back low score of 14 had to be over 25 to need chemo.

Thanks Pommy8

Hi @Abbydog
The ki67 score is only one part of the puzzle.
A lower score is better than a higher score just like a lower grade ( grade is 1 to 3) is better than a higher grade.
Also being hormone positive or having HER 2 is better than triple negative ( as there are extra targeted treatments for the first 2).
The size of the tumour and extent of lymph node involvement ( if any) is also important in deciding on treatment and prognosis.
That is why it is difficult to compare with others and your specialist medical team will come up with a treatment plan tailored to your own individual circumstances.
Take care 🌺

Hi everyone 
I’m following this chat with great interest as yesterday I had my first post op follow up appointment- not with my surgeon but with one of the assistant surgeons. I had a lumpectomy just over a week ago.
This was the first time the Ki67/chemotherapy discussion had come up for me as it was only something that had become evident post surgery.
So my Ki67 score was 15%. I had an invasive ductile carcinoma stage 2, 17mm in size, Her 2 neg and hormone receptive.
The doctor told me the MDT will discuss the result as they may recommend chemo - she told me it was because I was young (I’m 50) and it would be to stop a later recurrence…