Hi..i too have secondary cancer and have been on herceptin since feb 2010 (initially along with my 8 doses of chemo) & will continue indefinately. I understand what u mean about the 'reminder' and i also feel very tired on the afternoon and following day of treatment. I usually fall asleep 1/2 way home (we travel about 50 mins to get to treatment) and feel quite tired for another day. My family are used to me being sleepy now!! i don't think i get grumpy (u might have to check with the rest of the household) but maybe thats a sign of frustration for you???? Every now and then i have a down day and feel frustrated that i don't have an end date for treatment (yet!!)....maybe plan something nice for urself the following day, like a massage or facial, a movie, whatever is enjoyable for YOU..this way at least u can look forward to something special straight after treatment day..just a thought
Hope u have a great day
Sam :)