I've just finished 12 weekly Taxol. I had 4 AC dose dense every 2 weeks before the taxol which followed straight after. No break in between to notice too much of a difference except for the constant crying with Taxol. My joints feel like those of a rag doll. My knees and hips want to give way, I'm very unsteady on my feet. Mostly, I keep my feet up if I'm not sitting. Walking seems a thing of the past, even though my feet have stopped aching. I wouldn't wish it on anyone. Many don't make it to no 12 they told me. I asked for extra, lol. They said 12 was the max.