I was on Tamoxifen for five years from 2002 - 2007 (ages 34-39). After getting a new tumour last year (nine years later) I have been on Femara since January this year. Since I was still pre-menopausal, I got my ovaries removed and then started the Femara. Both my tumours were highly eostrogen sensitive. I have finished with all the hot flushes etc now, and the only annoying side effect from the Femara is stiffness and sore hips. If I keep active and take my fish/krill oil, it doesn't bother me too much. I had a double reconstruction using my lat-dorsi muscles 5 weeks ago, and overall, I feel pretty good. I'm 45 years old now. x Jane