@barney74 honestly, not even worth worrying about at this point, I was on Tamoxifen for 4yrs with zero side effects, and i mean nothing at all. 2nd diagnosis and post chemo however I was put on Arimidex and the thing is it's hard to say what the side effects are from, im guessing a combination of chemo, the medication and menopause. Im now on Aromasin but I promise, a little stiff but no big deal, doesn't stop me doing anything at all :) Once I was post chemo, I started Vitamin D and I take a scoop of magnesium in water daily, as it services over 300 enzymes in your body at a cell level and helps with pain. One step at a time xxx Melinda xo