@kmakm Tamoxifen is a receptor blocker, but other cells in the body with identical oestrogen receptors to the breast will also get starved of oestrogen – the ovary, pituitary gland, lining of the vagina.
Blocking of oestrogen in organs with receptors the same as the breast, e.g.ovary and pituitary glands, interfer- ing with the menstrual cycle and causing hot flushes and vaginal dryness as at menopause. These side effects are common at least initially. Depression, like that at natural menopause, may also be caused by blocking of oestrogen action in the brain.
all from
https://www.bcna.org.au/media/2220/10-beacon10.pdf I’m doing pretty well thanks, but next Sat will be 12 months since diagnosed. It’s been a brutal ride, but fingers crossed this year will be smoother sailing ⛵️ Hope your doing OK too.
Xx