Tamoxifen half strength effectiveness?
Seeking thoughts on 10 mg Tamoxifen efficacy versus the recommended 20 mg? Any studies been done on this? My onc has suggested to me that this drug has been around for 30 years with no consideration a...
Forum Discussion
Hi @Timba
Tamoxifen stinks for sure and you would think a drug that has been around for decades would have had some side effect tweeking by now huh?. Not sure how long you've been on it but for me it took 12 months before sleep came back to somewhat normal.
I'm not sure about 10mg studies , however, I am a member of a couple of Tamoxifen support facebook pages and the reduction to 10mg seems to be a very popular recommendation for the girls in the States who suffer greatly with SE's on the 20mg..
Then there is some study being done on the fact that it you don't have side effects is the drug working properly anyhow? There's another one about the efficency of 3 months on 3 months off. I run 3 months on, 1 month off for a reasonable balance.
Of course, no onc is going to recommend that but mine seems to think it's better than not taking it at all.
The choices and studies are endless. Damned if you do, damned if you don't and a multitude of confusion thrown in.
My percentage increase with the HT is also 3%. All these stats are averages so it could be anywhere between 0 and 6%. Who knows. I have spent a lot of time pondering whether it is worth the decrese in quality of life or not given that there is a 1 in 3 resistance rate any way and many people who have done all the right things still have a recurrence.
So, what to do????
Changing brands can help. I switched from Genox to Novladex after 18 months of hell on the first one. There was a significant difference. The SE's did not disappear but did calm down to a more managable level. It might be something to try.
It is a choice only you can make whether to continue or not. If you choose not and it comes back, can you live with that decision? Will you feel guilty and blame yourself if it returns or will you be satisified in your choice that it could have anyway and you did the best you could. That is the $64000 question and it is a hard one with no definitive answers.
Best of luck with your decision lovely.
xoxoxo
Tamoxifen stinks for sure and you would think a drug that has been around for decades would have had some side effect tweeking by now huh?. Not sure how long you've been on it but for me it took 12 months before sleep came back to somewhat normal.
I'm not sure about 10mg studies , however, I am a member of a couple of Tamoxifen support facebook pages and the reduction to 10mg seems to be a very popular recommendation for the girls in the States who suffer greatly with SE's on the 20mg..
Then there is some study being done on the fact that it you don't have side effects is the drug working properly anyhow? There's another one about the efficency of 3 months on 3 months off. I run 3 months on, 1 month off for a reasonable balance.
Of course, no onc is going to recommend that but mine seems to think it's better than not taking it at all.
The choices and studies are endless. Damned if you do, damned if you don't and a multitude of confusion thrown in.
My percentage increase with the HT is also 3%. All these stats are averages so it could be anywhere between 0 and 6%. Who knows. I have spent a lot of time pondering whether it is worth the decrese in quality of life or not given that there is a 1 in 3 resistance rate any way and many people who have done all the right things still have a recurrence.
So, what to do????
Changing brands can help. I switched from Genox to Novladex after 18 months of hell on the first one. There was a significant difference. The SE's did not disappear but did calm down to a more managable level. It might be something to try.
It is a choice only you can make whether to continue or not. If you choose not and it comes back, can you live with that decision? Will you feel guilty and blame yourself if it returns or will you be satisified in your choice that it could have anyway and you did the best you could. That is the $64000 question and it is a hard one with no definitive answers.
Best of luck with your decision lovely.
xoxoxo