So hard to really know. I thought I was sailing through A/C (no nausea, fatigue, nothing much) and did not like Taxol one bit as it affected my nose, my fingers, my feet, my tastebuds and so on but then I got a non Taxol side effect (belated A/C). Most of the Taxol side effects cleared up after the last treatment, peripheral neuropathy lingered but it's nearly 5 years since diagnosis, I think I am fine and that is the big thing, the main thing and sometimes the only thing!! Best of luck, 12 weeks can go pretty quickly if you grit your teeth and hang in there!