I really only got tired about halfway through radiation.I actually took time off work so I didn't have to worry.Perhaps you could negotiate with your boss.Some ladies worked reduced hours after the halfway mark but I guess it depends on your job. I have fair skin but it never blistered or broke down,just got very red.As soon as I was zapped,I would apply Aloe Vera gel over my boob and then a soft hankie to protect clothes. That night I would soak in a warm salt bath,pat my boob dry and apply vit E cream.The staff are great and will advise you on creams/medications.The redness is like bad sunburn.When you have finished radiation,it will still keep working for a further 2 weeks so you may not improve till after that.However,we all react differently to treatments and you may sail through it with no problems.Hope it is getting easier for you. Tonya xx