It depends a lot on how bad the osteoporosis is and what other options are available.
From the Women’s National Health Network (US)
Prolia, with the generic name Denosumab, is a type of monoclonal antibody, which stops the natural breakdown of bones. Prolia is injected two times per year. It should only be used if other treatment methods have failed or by post-menopausal women who have severe osteoporosis. The National Women’s Health Network suggests women try other FDA-approved osteoporosis medications prior to trying Prolia. This drug has a long list of side effects and it’s also important to note that long-term risks are unknown. The FDA Medication Guide lists the potential health problems, which include serious infections, thighbone fractures, and jaw bone problems. It is unclear if the benefits outweigh the risks.
My understanding, from my oncologist, is that any gains may be reversed if side effects result in stopping use of the drug. Jawbone problems can complicate any dental work. I know some people have found it very helpful but I think it’s worth a detailed discussion with an oncologist about specific benefits for an individual case.
