Hi @LMK74 I've been thinking about you and your decision about the trial. I just wanted to let you know I feel sooooo much better now my flu is easing. The Tamoxifen/Palbo combo is okay. My bloods were fine (mostly in the normal range) after 14 days. I am a little tired, achey, moody and have hot flushes, but I already had all this post chemo anyway. I think I can reasonably expect these side effects to ease with time and exercise/diet. I guess what I'm saying is, I will stay on the trial and if I had to make the choice again I would say yes. All the best xxxooo