Hi @CathyMac, it doesn't help when you are trying to get a new and unexpected part of your life in some sort of order but chemo effects are very variable and what works for one is different for another. I had the same regime, as @kezmusc says it's a frequently used cocktail. I had only one side effect from A/C which was at least partially caused by my age, and worked throughout both types of chemo. I actually had more irritation with Taxol, although most people find it easier. Your oncologist is being honest in indicating that side effects can make working hard or impossible, it's just not certain. One of the hardest things for treatment is to try and take one step at a time, rather than planning ahead. Planning makes us feel in control but it can be very hard if the plans don't quite work out. Best wishes.