Hi @Zan I take Arimidex and have been taking it for 7 months after swapping from letrozole. I have been taking an AI for a year. I will try to keep this short, but my oncologist is really keen to make sure I take an AI with the least side effects which is why I swapped. I still have stiff joints in the mornings, and again he is keen for me to give tamoxifen a try. In his words - less joint issues, much better for bones. I told him my concerns (which are based on what I have read on forums etc so not necessarily totally scientifically proven 🙂) that AI’s are much better etc. He said that there was a time when tamoxifen was the only drug available and it is still an excellent drug. He also said that it may be slightly below an AI, but not that much and if it meant better quality of life and less joint and bone issues, it is well worth thinking about taking. I guess basically he was really reassuring me that tamoxifen was still an excellent choice. One thing he said was that he didn’t want me ‘sucking up’ the issues until one day I just get fed up and refuse medication altogether - he tries to make sure I know there are alternatives and they are still really good choices.
Perhaps monitor your bone density really closely to see if the new regime is working, if not, switch to tamoxifen which is still an excellent medication. Take care
