Hi @Zan. My situation is similar to yours. I too have been on Letrozole for four and a half years and have osteopenia in my spine. I have always been a big exerciser doing weights a couple of times per week, dragon boat racing & Zumba and take Vitamin D suggested by my oncologist. But the only thing that has stabilised the osteopenia is 6 monthly Zometa infusions for bone strength. I am coming up to my 5th and will have 1 more after that, which my oncologist says have long lasting effects, hopefully enough to get me through 10 years of Letrozole. If you are doing ok on Arimidex you could try the exercise & bone strengtheners suggested by your oncologist but switch to Tamoxifen if you have further deterioration.
