Hi Tennille, I do not know what Pregablin is, but I have just finished Letrazole after 6 years, and had dexamethazone prior to each chemo round. The dexamethazone is given to help prevent side effects from the chemo. They give quite a large dose and it can make you a bit hyper, and sleeping can be hard. I was told to have them at 8am and then at 12md. My lovely oncologist prescribed sleeping pills, so I had no problems. Letrazole wasn't too bad, but there are some side effects like joint stiffness and skin dryness. These side effects do disappear in several months, so take things like fish oil to help your joints. After 6 years, I have just been switched back to tamoxifen, as I have now have low bone density. This is also a side effect of the drug, and I have kept up exercise, calcium and Vit D, but finally am almost osteoporotic. I also had hot flushes, but I was having them for 4 years prior to breast cancer, so don't think I can really blame Letrazole for them. This is still a great drug to use if menopausal, and I was happy to take it.
good luck with your treatment.
Chris xx