@Blondy was on anastozole for 3 years had minimal side effects the most being achy bones at night and the stiffness. So the letrozole was a real eye opener for me but in saying that I now seem to have settled down and getting muscle soreness but no achy bones, so I am able to cope with it now, panadol osteo Iโve been taking at night time and helps and am sleeping better too, been on it 3 weeks now so will preserver and see how I go, my oncologist did say when I mentioned the muscle soreness that it was a side effect and if got any worse let her know well it hasnโt got any worse itโs got better ๐