Sorry to hear about your mum. I lost my mum nearly 1 year to the day due to Dementia. I miss her terribly. Even though she wasn't aware of my illness the first time around, I could focus on her and sometimes forget my troubles. I personally had no trouble with Tamoxifen - was on it for nearly 4 years but had to change over to Arimidex when I had my second diagnosis in December 2010. We are all different but we don't have to put up with anything that is not working for us. As Tonya said talk with your doctor.XLeonie