Well @Hendrix ..didn't want to scare you. I had terrible joint pain a few days after chemo for around 24 to 48 hours. Mine was weekly chemo for 12 weeks so by around cycle 6 I was really fatigued, had a very sensitive stomach, couldn't tolerate fruit or spices. Vegetables tasted bitter. I had loose bowels (big diff to the constipation). I developed neuropathy in my feet and had balance issues. I had itchy skin and couldn't wear jewelry due to irritation or have a very hot showers. I had fluid issues/ oedema also. However...I got through it and most issues...bar some minor toe neuropathy resolved. My comment to the oncologist wasn't that it was better just different. The weekly thing made me miserable as no break. But hey...it is but a distant memory for me now. I hope you fair better. My friend had only some toe issues and that was it and right at the end. Kath