@sickgirl i started on Letrozole Sandoz last year. At about the 4 month mark my side effects reallt started to kick in and got worse over the next 3 months. Mostly joint pain and hot flushes. I didn't know you could change brands and possibly get different results. My med onc told me to stop taking them for a month to see what side effects were from the drug and what were just me going thru menopause as a result of my hysterectomy. I have now been on Exemestane (aromasin) Sandoz for about a month. Still getting similar side effects but nowhere near as bad. But I'm reserving final judgement until I get to the 4 month point again to see if I get cumulative effects again.