Hi there @Caccal.. and welcome to the group that nobody wants to join. In my case, chemo was a given as I had stage three, grade three, multifocal triple positive breast cancer with one node positive. I did ask my onco (large Sydney teaching hospital), about testing to see if chemo would make much of a difference and was told that based on the pathology reports on the biopsies so far taken, that the plan was chemo first..3 months AC followed by 12 weeks Taxol and Herceptin, with the Herceptin to continue for 11 months total. She said that there was some debate for the testing if it was stage 1 or borderline 2 and, most importantly no nodes involved. My chemo was then followed by bilateral mastectomy, sparing nothing and full axilliary clearance on the left, and sentinal nodes on the right. The pathology report on the removed breasts showed no active cancer detected anywhere, with only the dead tumour beds found. So, total zapping of any detectable cancer by the chemo. It was a very hard road to travel, I won't kid you there, but reading that pathology report whilst still bandaged up and with drains etc, made it all worth while. I'm now two years post diagnosis and No Evidence of Disease. Good luck with your ongoing treatment.Ally.